|
KMID : 0359320160560030139
|
|
Korean Journal of Veterinary Research
2016 Volume.56 No. 3 p.139 ~ p.145
|
|
|
Prognostic factors and efficacy of human intravenous immunoglobulin G in dogs with idiopathic immune-mediated hemolytic anemia: a retrospective study
|
|
Park So-Young
Kim Hak-Hyun
Kang Byeong-taek
Kang Ji-Houn
Yang Mhan-Pyo
|
|
|
Abstract
|
|
|
|
This study was conducted to determine the effect of treatment with intravenous human immunoglobulin G (hIVIgG) on outcome in dogs with idiopathic immune-mediated hemolytic anemia (IMHA), and to identify prognostic variables that determine outcome in affected dogs. Thirty-seven dogs that met the inclusion criteria were enrolled in a retrospective study. The dogs were categorized into two groups based on their having received hIVIgG. There was no significant difference in survival between the hIVIgG group and the non-hIVIgG group. Mortality during hospitalization and at 1 month, 1 year, or 2 years after discharge was not significantly different between the hIVIgG and the non-hIVIgG groups. Hemoglobinuria was significantly less prevalent in dogs that lived more than 1 year than in those who lived less than 1 year, and was less prevalent in dogs that lived more than 2 years than in those who lived less than 2 years. However, there was no difference in the presence of hemoglobinuria between dogs that lived less than 1 month and those that lived more than 1 month. Overall, there was no evidence of a beneficial effect of hIVIgG in dogs with idiopathic IMHA.
|
|
|
KEYWORD
|
|
|
autoimmune hemolytic anemia, canine, hemoglobinuria, mortality, seasonality
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|